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kw.\*:("Thymidylate synthase")

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Stacked beta-bulges in thymidylate synthase account for a novel right-handed rotation between opposing beta-sheetsMATTHEWS, D. A; APPELT, K; OATLEY, S. J et al.Journal of molecular biology. 1989, Vol 205, Num 2, pp 449-454, issn 0022-2836Article

A method for the determination of total, free, and 5-fluorodeoxyuridylate-bound thymidylate synthase in cell extractsFERNANDES, D. J; CRANFORD, S. K.Analytical biochemistry. 1984, Vol 142, Num 2, pp 378-385, issn 0003-2697Article

Evidence that a point mutation in dihydrofolate reductase―thymidylate synthase confers resistance to pyrimethamine in falciparum malariaPETERSON, D. S; WALLIKER, D; WELLEMS, T. E et al.Proceedings of the National Academy of Sciences of the United States of America. 1988, Vol 85, Num 23, pp 9114-9118, issn 0027-8424Article

SECONDARY ALPHA -HYDROGEN ISOTOPE EFFECTS ON THE INTERACTION OF 5-FLUORO-2'-DEOXYURIDYLATE AND 5,10-METHYLENETETRAHYDROFOLATE WITH THYMIDYLATE SYNTHETASEBRUICE TW; SANTI DV.1982; BIOCHEMISTRY (EASTON); ISSN 0006-2960; USA; DA. 1982; VOL. 21; NO 26; PP. 6703-6709; BIBL. 36 REF.Article

Antifolates targeted specifically to the folate receptorJACKMAN, Ann L; THETI, Davinder S; GIBBS, David D et al.Advanced drug delivery reviews. 2004, Vol 56, Num 8, pp 1111-1125, issn 0169-409X, 15 p.Article

Bacterial thymidylate synthase with intein, group II intron, and distinctive ThyX motifsLIU, Xiang-Qin; JING YANG.Journal of bacteriology. 2004, Vol 186, Num 18, pp 6316-6319, issn 0021-9193, 4 p.Article

Thymidylate synthase-dihydrofolate reductase in protozoaIVANETICH, K. M; SANTI, D. V.Experimental parasitology. 1990, Vol 70, Num 3, pp 367-371, issn 0014-4894Article

The thymidylate synthesis cycle and anticancer drugsDOUGLAS, K. T.Medicinal research reviews (Print). 1987, Vol 7, Num 4, pp 441-475, issn 0198-6325Article

Alternative thymidylate synthase,ThyX, involved in Corynebacterium glutamicum ATCC 13032 survival during stationary growth phasePARK, Mijeong; CHO, Sukhyeong; LEE, Hosa et al.FEMS microbiology letters. 2010, Vol 307, Num 2, pp 128-134, issn 0378-1097, 7 p.Article

CATALYTIC FUNCTION OF THYMIDYLATE SYNTHASE IS CONFINED TO S PHASE DUE TO ITS ASSOCIATION WITH REPLITASEREDDY GPV.1982; BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; ISSN 0006-291X; USA; DA. 1982; VOL. 109; NO 3; PP. 908-915; BIBL. 14 REF.Article

Enhanced inhibition of thymidylate synthase by methotrexate polyglutamatesALLEGRA, C. J; CHABNER, B. A; DRAKE, J. C et al.The Journal of biological chemistry (Print). 1985, Vol 260, Num 17, pp 9720-9726, issn 0021-9258Article

Comparison of characteristics of thymidylate synthases isolated from eukaryotic and prokaryotic cellsSLAVIKOVA, V; SLAVIK, K; MOTYCKA, K et al.Collection of Czechoslovak chemical communications. 1984, Vol 49, Num 3, pp 743-751, issn 0010-0765Article

Mechanisms of action of FdUMP[10] : Metabolite activation and thymidylate synthase inhibitionBIJNSDORP, I. V; COMIJN, E. M; PADRON, J. M et al.Oncology reports. 2007, Vol 18, Num 1, pp 287-291, issn 1021-335X, 5 p.Article

The thymidylate synthase tandem repeat polymorphism is not associated with homocysteine concentrations in healthy young subjectsBROWN, Karen S; KLUIJTMANS, Leo A. J; STRAIN, J. J et al.Human genetics. 2004, Vol 114, Num 2, pp 182-185, issn 0340-6717, 4 p.Article

An alternative flavin-dependent mechanism for thymidylate synthesisMYLLYKALLIO, Hannu; LIPOWSKI, Gerard; LEDUC, Damien et al.Science (Washington, D.C.). 2002, Vol 297, Num 5578, pp 105-107, issn 0036-8075Article

Antitumor activity of fluoropyrimidines and thymidylate synthetase inhibitionKUBOTA, T; FUJITA, S; FUSE, M et al.Japanese journal of cancer research. 1991, Vol 82, Num 4, pp 476-482, issn 0910-5050Article

Inhibition of thymidylate synthase by glyceraldehyde 3-phosphateBURES, A. K; DARON, H. H; AULL, J. L et al.International journal of biochemistry. 1991, Vol 23, Num 7-8, pp 733-736, issn 0020-711X, 4 p.Article

Microcalorimetric study of the binding of methotrexate and its metabolites to thymidylate synthase : a new method for affinity constant determinationSARI, J. C; GILLI, R; LOPEZ, C et al.Journal of thermal analysis. 1991, Vol 37, Num 8, pp 1897-1903, issn 0368-4466Article

Regional assignment of the human thymidylate synthase (TS) gene to chromosome band 18p11.32 by nonisotopic in situ hybridizationHORI, T.-A; TAKAHASHI, E.-I; AYUSAWA, D et al.Human genetics. 1990, Vol 85, Num 6, pp 576-580, issn 0340-6717, 5 p.Article

Dépendance vis-à-vis de la thymine et de la thymidine chez des mutants de Yersinia pestis ayant une thymidylate synthétase altéréeMISHAN'KIN, B. N; KRAVCHENKO, A. N; MAJSKIJ, V. G et al.Žurnal mikrobiologii, èpidemiologii i immunobiologii. 1989, Num 2, pp 24-29, issn 0372-9311Article

A stable binary complex between Leishmania major thymidylate synthase and the substrate deoxyuridylate. A slow-binding interactionGARVEY, E. P; SANTI, D. V.The Journal of biological chemistry (Print). 1987, Vol 262, Num 19, pp 9068-9074, issn 0021-9258Article

Salmonella typhimurium thyA mutants fail to grow intracellularly in vitro and are attenuated in miceKOK, Menno; BÜHLMANN, Elisabeth; PECHERE, Jean-Claude et al.Microbiology (Reading). 2001, Vol 147, pp 727-733, issn 1350-0872, 3Article

Interaction of 2-thio-5-fluoro-dUMP and 4-thio-5-fluoro-dUMP with mammalian normal and tumour and helminthic thymidylate synthases : influence of C(4)-substituents on specificity for enzyme inactivationDZIK, J. M; ZIELINSKI, Z; CIESLA, J et al.Biochemical and biophysical research communications (Print). 1993, Vol 195, Num 3, pp 1301-1308, issn 0006-291XArticle

Effects of methotrexate on rat liver regeneration after partial hepatectomyTSUKAMOTO, I; KOJO, S.Clinical science (1979). 1992, Vol 82, Num 2, pp 181-184, issn 0143-5221Article

Developments of the fluoropyrimidines as inhibitors of thymidylate synthetase : pharmacologic and clinical aspectsMACHOVER, D.Journal of surgical oncology. 1991, pp 42-50, issn 0022-4790, SUP2Article

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